Biotechnology and Tissue Engineering

Biotechnology and Tissue Engineering Micropatterning and the effects
of micro- and nano-structured surfaces on stem cell fate

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Biotechnology and Tissue Engineering. The assignment is a literature review, making up part of a lab report
which aims to:
– To understand the effects of varying functionalisation of
micro-patterned substrates on mesenchymal stem cell differentiation (the
functionalisation proteins compared in the project are collagen and
fibronectin, so specific research into this would be appropriate)
– To determine which factors drive mesenchymal stem cell differentiation
(topography vs functionalisation. The osteogenic lineage is assessed in
this project, so specific research into this is appropriate)
(I can provide a PowerPoint for clarification if wanted)There are a few
questions that need to be answered (maybe a couple more, I’ll message
them tomorrow)
-What is micropatterning?
-Why is it important?
-What is it used for?
-Specific Applications