Pathophysiology, Diagnosis, Medical Management and Clinical Manifestations of Asthma

 

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Pathophysiology, Diagnosis, Medical Management and Clinical Manifestations of Asthma

Asthma is one of the major chronic respiratory conditions which alter the respiratory function of the body. The World Health Organisation or WHO (2012) defines asthma as a chronic inflammatory disease of the airways characterised by frequent episodes of breathlessness and wheezing. This difficulty in breathing is caused by the swelling and constricting of the airways. Exposure to allergens, pollutants, cold air, infection and exercise can increase the risk of asthmatics having an attack (Funnel, Koutoukidis and Lawrence 2009).

Pathophysiology, Diagnosis, Medical Management and Clinical Manifestations of Asthma

This essay will discuss on the pathophysiology, diagnosis, medical management and clinical manifestations of asthma. It will also cover the client education needed to provide for those with asthma, asthma’s risk factors and its prognosis. According to the National Asthma Council of Australia or NACA (2006) more than 2.2 million Australians are suffering from asthma. This essay will therefore also describe how asthma impacts on its victims and their life style.

Pathophysiology, Diagnosis, Medical Management and Clinical Manifestations of Asthma

Kaufman (2011) describes the pathophysiology of asthma as a pathologic condition which affects the lower respiratory tract by narrowing the airways as a result of epithelial damage, excessive mucus production, oedema, bronchoconstriction and muscle damage.

Pathophysiology, Diagnosis, Medical Management and Clinical Manifestations of Asthma

In asthma the cells in the epithelium layer can be destroyed and peel away, making the respiratory tract more susceptible to allergens and infections, thereby contributing to airway hyper-responsiveness (Kaufman 2011). Asthma also triggers the development of mucus cells and mucus glands. This increases mucus production, thus forming mucous plugs which can obstruct the airways (Monahan et al. 2007).

Pathophysiology, Diagnosis, Medical Management and Clinical Manifestations of Asthma

Airway oedema is another change that occurs in the respiratory tract due to asthma. It involves the dilation and leaking of capillaries in the airway walls which limits airflow (Kaufman 2011). Monahan et al. (2007) add that increased capillary permeability and leakage can obstruct the airways due to swelling. They also explain that the inflammatory agents such as histamine, tryptase, leukotriences and prostaglandins act on smooth muscles of airway walls and cause bronchoconstriction which restricts the airflow to alveoli.

 

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